Multi-Objective Optimization of Engineered Injection and Extraction to Enhance In Situ Remediation of Contaminated Groundwater Multi-objective evolutionary algorithms (MOEAs) are used to optimize the performance of solutions to complex design problems based on objectives established by decision-makers. This study contributes an iterative problem reformulation technique for MOEA decision support. Problem formulations consist of objectives, decision variables, and constraints, and directly influence the results generated by the MOEA. Typically, design problems are optimized based on a single problem formulation established a priori. In this paper, we demonstrate an approach to perform iterative optimization using problem formulations updated from analyses of results from prior rounds of optimization, which often reveal design components that were not initially considered. To demonstrate the approach, we consider a novel groundwater remediation technique, Engineered Injection and Extraction (EIE), which has never been optimized in the literature. Iterative problem reformulation enabled the MOEA to generate EIE solutions with better performance than the heuristically-developed solution used in prior work.